Synthesis and discovery of 18α-GAMG as anticancer agent in vitro and in vivo via down expression of protein p65
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep07106.pdf
Reference21 articles.
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2. Paul, A. et al. Stabilization and structural alteration of the G-quadruplex DNA made from the human telomeric repeat mediated by Troger's base based novel benzimidazole derivatives. J Med Chem 55, 7460–7471 (2012).
3. Paul, A. et al. Binding of gemini bisbenzimidazole drugs with human telomeric G-quadruplex dimers: effect of the spacer in the design of potent telomerase inhibitors. PLoS One 7, e39467 (2012).
4. Singh, M. et al. Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol Cell 47, 16–26 (2012).
5. Hahn, W. C. et al. Inhibition of telomerase limits the growth of human cancer cells. Nat Med 5, 1164–1170 (1999).
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