Evolved Cas9 variants with broad PAM compatibility and high DNA specificity-Reference-Cited by-同舟云学术

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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

Published:2018-02-28 Issue:7699 Volume:556 Page:57-63
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Hu Johnny H.,Miller Shannon M.,Geurts Maarten H.,Tang Weixin,Chen Liwei,Sun Ning,Zeina Christina M.,Gao Xue,Rees Holly A.,Lin Zhi,Liu David R.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature26155.pdf

Reference40 articles.

1. Doudna, J. A. & Charpentier, E. Genome editing. The new frontier of genome engineering with CRISPR–Cas9. Science 346, 1258096 (2014)

2. Hsu, P. D., Lander, E. S. & Zhang, F. Development and applications of CRISPR–Cas9 for genome engineering. Cell 157, 1262–1278 (2014)

3. Mitsunobu, H., Teramoto, J., Nishida, K. & Kondo, A. Beyond native Cas9: manipulating genomic information and function. Trends Biotechnol. 35, 983–996 (2017)

4. Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A. & Liu, D. R. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature 533, 420–424 (2016)

5. Gaudelli, N. M. et al. Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage. Nature 551, 464–471 (2017)

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