Targeted therapy in penile cancer: a new treatment paradigm
Author:
Publisher
Springer Science and Business Media LLC
Subject
Urology
Link
http://www.nature.com/articles/nrurol.2017.183.pdf
Reference10 articles.
1. Christodoulidou, M., Sahdev, V., Houssein, S. & Muneer, A. Epidemiology of penile cancer. Curr. Probl. Cancer 39, 126–136 (2015).
2. Chipollini, J. et al. Advances in understanding of penile carcinogenesis: the search for actionable targets. Int. J. Mol. Sci. 18, 1777 (2017).
3. Necchi, A. et al. First-line therapy with dacomitinib, an orally available pan-HER tyrosine kinase inhibitor, for locally-advanced or metastatic penile squamous cell carcinoma: results of an open label, single-arm, single-center, phase 2 study. BJU Int. http://dx.doi.org/10.1111/bju.14013 (2017).
4. Stankiewicz, E. et al. Alternative HER/PTEN/Akt pathway activation in HPV positive and negative penile carcinomas. PLoS ONE 6, e17517 (2011).
5. Chaux, A. et al. The epidermal growth factor receptor is frequently overexpressed in penile squamous cell carcinomas: a tissue microarray and digital image analysis study of 112 cases. Hum. Pathol. 44, 2690–2695 (2013).
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