Poor trial accrual hinders germ cell tumor therapy advances
Author:
Publisher
Springer Science and Business Media LLC
Subject
Urology
Link
http://www.nature.com/articles/nrurol.2012.59.pdf
Reference10 articles.
1. Williams, S. D. et al. Treatment of disseminated germ-cell tumors with cisplatin, bleomycin, and either vinblastine or etoposide. N. Engl. J. Med. 316, 1435–1440 (1987).
2. International Germ Cell Cancer Collaborative Group (IGCCCG). International germ cell consensus classification: a prognosis factor-based staging system for metastatic germ cell cancers. J. Clin. Oncol. 15, 594–603 (1997).
3. Motzer, R. J. et al. Phase III randomized trial of conventional-dose chemotherapy with or without high-dose chemotherapy and autologous hematopoietic stem-cell rescue as first-line treatment for patients with poor-prognosis metastatic germ cell tumors. J. Clin. Oncol. 25, 247–256 (2007).
4. Daugaard, G. et al. A randomized phase III study comparing standard dose BEP with sequential high-dose cisplatin, etoposide, and ifosfamide (VIP) plus stem-cell support in males with poor-prognosis germ-cell cancer. An intergroup study of EORTC, GTCSG, and Grupo Germinal (EORTC 30974). Ann. Oncol. 22, 1054–1061 (2010).
5. de Wit, R. et al. Randomized phase III study comparing paclitaxel-bleomycin, etoposide, and cisplatin (BEP) to standard BEP in intermediate-prognosis germ-cell cancer: intergroup study EORTC 30983. J. Clin. Oncol. 30, 792–799 (2012).
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