Insertional mutagenesis in mice: new perspectives and tools
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg1638.pdf
Reference101 articles.
1. Nadeau, J. H. et al. Sequence interpretation. Functional annotation of mouse genome sequences. Science 291, 1251–1255 (2001).
2. Austin, C. P. et al. The knockout mouse project. Nature Genet. 36, 921–924 (2004).
3. Auwerx, J. et al. The European dimension for the mouse genome mutagenesis program. Nature Genet. 36, 925–927 (2004). References 1–3 outline the goals and approaches to be used to achieve complete functional annotation of the mouse genome through mutagenesis and phenotype analysis. Reference 1 describes the establishment of the IMMC, and references 2 and 3 are a further refinement of approaches and goals that reflect the thoughts of the mouse community today.
4. Justice, M. J., Noveroske, J. K., Weber, J. S., Zheng, B. & Bradley, A. Mouse ENU mutagenesis. Hum. Mol. Genet. 8, 1955–1963 (1999).
5. Hrabe de Angelis, M. H. et al. Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nature Genet. 25, 444–447 (2000).
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