The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia
Author:
Funder
Irish Research Council
Science Foundation Ireland
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health,Pharmacology
Link
http://www.nature.com/articles/s41386-019-0410-z.pdf
Reference45 articles.
1. Ripke S, Neale BM, Corvin A, Walters JT, Farh KH, Holmans PA, et al. Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014;511:421–7.
2. Mitchell KJ. The genetics of neurodevelopmental disorders. Hoboken, NJ, USA: John Wiley & Sons; 2015.
3. Purcell S, Wray N, Stone J, Visscher P, O’Donovan M, Sullivan P, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460:748–52.
4. Nicodemus KK, Hargreaves A, Morris D, Anney R, Gill M, Corvin A, et al. Variability in working memory performance explained by epistasis vs olygenic scores in the ZNF804A pathway. JAMA Psychiatry. 2014;71:778.
5. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci. 2005;102:15545–50.
Cited by 47 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Network-wide risk convergence in gene co-expression identifies reproducible genetic hubs of schizophrenia risk;Neuron;2024-09
2. Discovering functional interactions among schizophrenia-risk genes by combining behavioral genetics with cell biology;Neuroscience & Biobehavioral Reviews;2024-09
3. Cell-type-specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in Alzheimer’s disease;Nature Communications;2023-11-30
4. A genome-wide association scan reveals novel loci for facial traits of Koreans;Genomics;2023-11
5. Recent natural selection conferred protection against schizophrenia by non-antagonistic pleiotropy;Scientific Reports;2023-09-19
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3