Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study

Author:

Martinez Diana,Slifstein Mark,Matuskey David,Nabulsi Nabeel,Zheng Ming-Qiang,Lin Shu-fei,Ropchan Jim,Urban Nina,Grassetti Alexander,Chang Dinnisa,Salling Michael,Foltin Richard,Carson Richard E.,Huang Yiyun

Funder

U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse

Publisher

Springer Science and Business Media LLC

Subject

Psychiatry and Mental health,Pharmacology

Reference55 articles.

1. Koob GF. Neurobiological substrates for the dark side of compulsivity in addiction. Neuropharmacology. 2009;56:18–31.

2. Trifilieff P, Martinez D. Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence. Front Psychiatry. 2013;4:44.

3. Shippenberg TS, Herz A. Differential effects of mu and kappa opioid systems on motivational processes. NIDA Res Monogr. 1986;75:563–6.

4. Sivam SP. Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism. J Pharmacol Exp Ther. 1989;250:818–24.

5. Smiley PL, Johnson M, Bush L, Gibb JW, Hanson GR. Effects of cocaine on extrapyramidal and limbic dynorphin systems. J Pharmacol Exp Ther. 1990;253:938–43.

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