A unique role for cAMP signaling in microglia during opioid tolerance and withdrawal
Author:
Funder
U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health,Pharmacology
Link
https://www.nature.com/articles/s41386-023-01685-2.pdf
Reference6 articles.
1. Nestler EJ. Reflections on: “A general role for adaptations in G-Proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function”. Brain Res. 2016;1645:71–74.
2. Le Merrer J, Befort K, Gardon O, Filliol D, Darcq E, Dembele D, et al. Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network. Addic Biol. 2012;17:1–12.
3. Maduna T, Audouard E, Dembélé D, Mouzaoui N, Reiss D, Massotte D, et al. Microglia express mu opioid receptor: insights from transcriptomics and fluorescent reporter mice. Front Psychiatry. 2019;9:726.
4. Coffey KR, Lesiak AJ, Marx RE, Vo EK, Garden GA, Neumaier JF. A cAMP-related gene network in microglia is inversely regulated by morphine tolerance and withdrawal. Biol Psychiatry Glob Open Sci. 2022;2:180–9.
5. Bernier LP, Bohlen CJ, York EM, Choi HB, Kamyabi A, Dissing-Olesen L, et al. Nanoscale surveillance of the brain by microglia via cAMP-regulated filopodia. Cell Rep. 2019;27:2895–908.
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