A diffusion MRI tractography atlas for concurrent white matter mapping across Eastern and Western populations

Author:

Li YijieORCID,Zhang Wei,Wu Ye,Yin Li,Zhu Ce,Chen Yuqian,Cetin-Karayumak SuheylaORCID,Cho Kang Ik K.,Zekelman Leo R.,Rushmore Jarrett,Rathi Yogesh,Makris Nikos,O’Donnell Lauren J.ORCID,Zhang FanORCID

Abstract

AbstractThe study of brain differences across Eastern and Western populations provides vital insights for understanding potential cultural and genetic influences on cognition and mental health. Diffusion MRI (dMRI) tractography is an important tool in assessing white matter (WM) connectivity and brain tissue microstructure across different populations. However, a comprehensive investigation into WM fiber tracts between Eastern and Western populations is challenged due to the lack of a cross-population WM atlas and the large site-specific variability of dMRI data. This study presents a dMRI tractography atlas, namely the East-West WM Atlas, for concurrent WM mapping between Eastern and Western populations and creates a large, harmonized dMRI dataset (n=306) based on the Human Connectome Project and the Chinese Human Connectome Project. The curated WM atlas, as well as subject-specific data including the harmonized dMRI data, the whole brain tractography data, and parcellated WM fiber tracts and their diffusion measures, are publicly released. This resource is a valuable addition to facilitating the exploration of brain commonalities and differences across diverse cultural backgrounds.

Publisher

Springer Science and Business Media LLC

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