Genetic analysis of chemoresistance in primary murine lymphomas

Author:

Schmitt Clemens A.,Rosenthal Christine T.,Lowe Scott W.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference35 articles.

1. Brown, J.M. & Wouters, B.G. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res. 59, 1391–1399 (1999).

2. Schmitt, C.A., McCurrach, M.E., de Stanchina, E., Wallace-Brodeur, R.R. & Lowe, S.W. INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. Genes Dev. 13, 2670–2677 (1999).

3. Bearss, D.J. et al. Genetic determinants of response to chemotherapy in transgenic mouse mammary and salivary tumors. Oncogene 19, 1114–1122 (2000).

4. Omer, C.A. et al. Mouse mammary tumor virus-ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor. Cancer Res. 60, 2680–2688 (2000).

5. Adams, J.M. et al. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature 318, 533–538 (1985).

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