TNFerade Biologic: Preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene

Author:

Rasmussen Henrik,Rasmussen Camilla,Lempicki Maria,Durham Rebecca,Brough Douglas,King C Richter,Weichselbaum Ralph

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Reference34 articles.

1. Balkwell FR, Lee A, Aldam G et al. Human tumor xenografts treated with recombinant human tumor necrosis factor alone or in combination with interferon Cancer Res 1996 46: 3990–3993

2. Asher A, Mule JJ, Reichert CM et al. Studies on the anti-tumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo J Immunol 1987 138: 963–974

3. Renard N, Lienard D, Lespagnard L et al. Early endothelium activation and polymorphonuclear cell invasion precede specific necrosis of human melanoma and sarcoma treated by intravascular high-dose tumor necrosis factor alpha (rTNA alpha) Int J Cancer 1994 57: 656–663

4. Fukumura D, Salehi HA, Witwer B et al. Tumor necrosis factor alpha–induced leukocyte adhesion in normal and tumor vessels: effect of tumor type, transplantation site, and host strain Cancer Res 1995 55: 4824–4829

5. Hallahan DE, Vokes EE, Rubin SJ et al. Phase I dose-escalation study of tumor necrosis factor-alpha and concomitant radiation therapy Cancer J Sci Am 1995 1: 204–209

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