Development of an inducible suicide gene system based on human caspase 8-Reference-Cited by-同舟云学术

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Development of an inducible suicide gene system based on human caspase 8

Published:2005-03-04 Issue:7 Volume:12 Page:627-639
ISSN:0929-1903
Container-title:Cancer Gene Therapy
language:en
Short-container-title:Cancer Gene Ther

Author:

Carlotti Françoise,Zaldumbide Arnaud,Martin Patrick,Boulukos Kim E,Hoeben Rob C,Pognonec Philippe

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/7700825.pdf

Reference54 articles.

1. van Dillen IJ, Mulder NH, Vaalburg W, et al. Influence of the bystander effect on HSV-tk/GCV gene therapy. A review. Curr Gene Ther. 2002;2:307–322.

2. Tomicic MT, Thust R, Kaina B . Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: critical role of DNA breaks, Bcl-2 decline and caspase-9 activation. Oncogene. 2002;21:2141–2153.

3. van der Eb MM, Geutskens SB, van Kuilenburg AB, et al. Ganciclovir nucleotides accumulate in mitochondria of rat liver cells expressing the herpes simplex virus thymidine kinase gene. J Gene Med. 2003;5:1018–1027.

4. Mullen CA, Anderson L, Woods K, et al. Ganciclovir chemoablation of herpes thymidine kinase suicide gene-modified tumors produces tumor necrosis and induces systemic immune responses. Hum Gene Ther. 1998;9:2019–2030.

5. Thomis DC, Marktel S, Bonini C, et al. A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease. Blood. 2001;97:1249–1257.

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