A minimum c-erbB-2 promoter-mediated expression of herpes simplex virus thymidine kinase gene confers selective cytotoxicity of human breast cancer cells to ganciclovir

Author:

Maeda Tomoko,O-Wang Jiyang,Matsubara Hisahiro,Asano Takehide,Ochiai Takenori,Sakiyama Shigeru,Tagawa Masatoshi

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Reference25 articles.

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2. Moolten FL, Wells JM . Curability of tumors bearing herpes thymidine kinase genes transferred by retrovirus vectors J Natl Cancer Inst 1990 82: 297–300

3. Freeman SM, Abboud CN, Whartenby KA, et al . The “bystander effect”: tumor regression when a fraction of the tumor mass is genetically modified Cancer Res 1993 53: 5274–5283

4. Miller N, Whelan J . Progress in transcriptionally targeted and regulatable vectors for genetic therapy Hum Gene Ther 1997 8: 803–815

5. Mawatari F, Tsuruta S, Ido A, et al . Retrovirus-mediated gene therapy for hepatocellular carcinoma: selective and enhanced suicide gene expression regulated by human α-fetoprotein enhancer directly linked to its promoter Cancer Gene Ther 1998 5: 301–306

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