Th2-dominated antitumor immunity induced by DNA immunization with the genes coding for a basal core peptide PDTRP and GM-CSF
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/7700913.pdf
Reference48 articles.
1. Ulmer J, Donnelly J, Parker S, Rhodes GH, Felgner PL, Dwarki VJ et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993; 259: 1745–1749.
2. Pu O-U, Hwang L-H, Tao M-H, Chiang BL, Chen DS . Co-delivery of GM-CSF gene enhances the immune responses of hepatitis C viral core protein expressing DNA vaccine: role of dendritic cells. J Med Virol 2002; 66: 320–323.
3. Wang B, Merva M, Dang K, Ugen KE, Williams WV, Weiner DB . Immunization by direct DNA inoculation induces rejection of tumor cell challenge. Hum Gene Ther 1995; 6: 407–418.
4. Fynan E, Webster R, Fuller D, Haynes JR, Santoro JC, Robinson HL . DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc Natl Acad Sci USA 1993; 90: 11478–11482.
5. Ye M, Morello CS, Spector DH . Multiple epitopes in the murine cytomegalovirus early gene product M84 are efficiently presented in infected primary macrophages and contribute to strong CD8+-T-lymphocyte responses and protection following DNA immunization. J Virol 2004; 78: 11233–11245.
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