Efficacy of the bystander effect in the herpes simplex virus thymidine kinase-mediated gene therapy is influenced by the expression of connexin43 in the target cells

Author:

Namba Hiroki,Iwadate Yasuo,Kawamura Kiyoko,Sakiyama Shigeru,Tagawa Masatoshi

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Reference29 articles.

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2. Caruso M, Panis Y, Gagandeep S, Houssin D, Salzmann J-L, Klatzmann D . Regression of established macroscopic liver metastases after in situ transduction of a suicide gene Proc Natl Acad Sci USA 1993 90: 7024–7028

3. Barba D, Hardin J, Sadelain M, Gage FH . Development of anti-tumor immunity following thymidine kinase–mediated killing of experimental brain tumor Proc Natl Acad Sci USA 1994 91: 4348–4352

4. Gagandeep S, Brew R, Green B, et al . Prodrug-activated gene therapy: involvement of an immunological component in the “bystander effect.” Cancer Gene Ther 1996 3: 83–88

5. Samejima Y, Meruelo D . “Bystander killing” induces apoptosis and is inhibited by forskolin Gene Ther 1995 2: 50–58

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