Interferon α2b gene delivery using adenoviral vector causes inhibition of tumor growth in xenograft models from a variety of cancers

Author:

Iqbal Ahmed C M,Johnson Duane E,Demers G William,Engler Heidren,Howe John A,Wills Ken N,Wen Shu-Fen,Shinoda Jeremy,Beltran Josie,Nodelman Margarita,Machemer Todd,Maneval Dan C,Nagabhushan Tatanahalli L,Sugarman Barry J

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Reference26 articles.

1. Bordens R, Grossberg SE, Trotta PP, et al . Molecular and biologic characterization of interferon α2b Semin Oncol 1987 24: 41–51

2. Gutterman JU . Cytokine therapeutics: lessons from interferon α Proc Natl Acad Sci USA 1994 91: 1198–1205

3. Pfeffer LM, Dinarrello CA, Herberman RB, et al . Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons Cancer Res 1998 58: 2489–2499

4. Einhorn S, Grander D . Why do so many cancer patients fail to respond to interferon therapy J Interferon Cytokine Res 1996 16: 275–281

5. Gutterman JU, Fine S, Quesada J, et al . Recombinant leukocyte A interferon: pharmacokinetics, single-dose tolerance and biologic effect in cancer patients Ann Intern Med 1982 96: 549–556

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