Defining and improving the genome-wide specificities of CRISPR–Cas9 nucleases
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg.2016.28.pdf
Reference95 articles.
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3. Evans, M. J. & Kaufman, M. H. Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154–156 (1981).
4. The 2007 Nobel Prize in Physiology or Medicine - Press Release. Nobelprize.org [online]
5. Rouet, P., Smih, F. & Jasin, M. Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol. Cell. Biol. 14, 8096–8106 (1994). This study first demonstrated that nuclease-induced DSBs could stimulate homologous recombination.
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