Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex-Reference-Cited by-同舟云学术

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Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

Published:2001-03 Issue:3 Volume:2 Page:229-234
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Kalergis Alexis M.,Boucheron Nicole,Doucey Marie-Agnés,Palmieri Edith,Goyarts Earl C.,Vegh Zsuzsanna,Luescher Immanuel F.,Nathenson Stanley G.

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni0301_229.pdf

Reference47 articles.

1. Joyce, S. & Nathenson, S. G. Alloreactivity, antigen recognition and T-cell selection: three diverse T-cell recognition problems with a common solution. Immunol. Rev. 154, 59–103 (1996).

2. Garcia, K. C., Teyton, L. & Wilson, I. A. Structural basis of T cell recognition. Annu. Rev. Immunol. 17, 369–397 (1999).

3. Sykulev, Y., Joo, M., Vturina, I., Tsomides, T. J. & Eisen, H. N. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity. 4, 565–571 (1996).

4. Eisen, H. N., Sykulev, Y. & Tsomides, T. J. Antigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins. Adv. Protein Chem. 49, 1–56 (1996).

5. Valitutti, S. & Lanzavecchia, A. Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition. Immunol. Today 18, 299–304 (1997).

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