Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes-Reference-Cited by-同舟云学术

Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes

Published:2015-06-15 Issue:7 Volume:21 Page:760-768
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Xue Ruidan,Lynes Matthew D,Dreyfuss Jonathan M,Shamsi Farnaz,Schulz Tim J^ORCID,Zhang Hongbin,Huang Tian Lian,Townsend Kristy L,Li Yiming,Takahashi Hirokazu,Weiner Lauren S^ORCID,White Andrew P,Lynes Maureen S,Rubin Lee L,Goodyear Laurie J,Cypess Aaron M,Tseng Yu-Hua

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3881.pdf

Reference51 articles.

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3. Guerra, C., Koza, R.A., Yamashita, H., Walsh, K. & Kozak, L.P. Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. J. Clin. Invest. 102, 412–420 (1998).

4. Petrovic, N. et al. Chronic peroxisome proliferator-activated receptor gamma (PPARγ) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J. Biol. Chem. 285, 7153–7164 (2010).

5. Harms, M. & Seale, P. Brown and beige fat: development, function and therapeutic potential. Nat. Med. 19, 1252–1263 (2013).

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