Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry
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Published:2018-06-05
Issue:1
Volume:4
Page:
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ISSN:2056-5968
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Container-title:Cell Discovery
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language:en
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Short-container-title:Cell Discov
Author:
Yang Shu, Xu Miao, Lee Emily M, Gorshkov KirillORCID, Shiryaev Sergey A., He Shihua, Sun Wei, Cheng Yu-Shan, Hu Xin, Tharappel Anil Mathew, Lu Billy, Pinto Antonella, Farhy Chen, Huang Chun-Teng, Zhang Zirui, Zhu Wenjun, Wu Yuying, Zhou Yi, Song Guang, Zhu HengORCID, Shamim Khalida, Martínez-Romero Carles, García-Sastre Adolfo, Preston Richard A., Jayaweera Dushyantha T., Huang Ruili, Huang Wenwei, Xia Menghang, Simeonov Anton, Ming GuoliORCID, Qiu Xiangguo, Terskikh Alexey V., Tang Hengli, Song Hongjun, Zheng WeiORCID
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry
Reference51 articles.
1. Ming, G. L., Tang, H. & Song, H. Advances in zika virus research: stem cell models, challenges, and opportunities. Cell Stem. Cell 19, 690–702 (2016). 2. Mlakar, J. et al. Zika virus associated with microcephaly. N. Engl. J. Med. 374, 951–958 (2016). 3. Organization, W. H. Ebola Outbreak 2014–2015
http://www.who.int/csr/disease/ebola/en/ 4. Sweiti, H., Ekwunife, O., Jaschinski, T. & Lhachimi, S. K. Repurposed therapeutic agents targeting the ebola virus: a systematic review. Curr. Ther. Res. Clin. Exp. 84, 10–21 (2017). 5. Madrid, P. B. et al. Evaluation of Ebola virus inhibitors for drug repurposing. ACS Infect. Dis. 1, 317–326 (2015).
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