Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response-Reference-Cited by-同舟云学术

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Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response

Published:2008-11-21 Issue:3 Volume:16 Page:449-464
ISSN:1350-9047
Container-title:Cell Death & Differentiation
language:en
Short-container-title:Cell Death Differ

Author:

Moisoi N,Klupsch K,Fedele V,East P,Sharma S,Renton A,Plun-Favreau H,Edwards R E,Teismann P,Esposti M D,Morrison A D,Wood N W,Downward J,Martins L M

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/cdd2008166.pdf

Reference36 articles.

1. Faccio L, Fusco C, Chen A, Martinotti S, Bonventre JV, Zervos AS . Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia. J Biol Chem 2000; 275: 2581–2588.

2. Ekert PG, Vaux DL . The mitochondrial death squad: hardened killers or innocent bystanders? Curr Opin Cell Biol 2005; 17: 626–630.

3. Jones JM, Datta P, Srinivasula SM, Ji W, Gupta S, Zhang Z et al. Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice. Nature 2003; 425: 721–727.

4. Martins LM, Morrison A, Klupsch K, Fedele V, Moisoi N, Teismann P et al. Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice. Mol Cell Biol 2004; 24: 9848–9862.

5. Strauss KM, Martins LM, Plun-Favreau H, Marx FP, Kautzmann S, Berg D et al. Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet 2005; 14: 2099–2111.

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