Gene expression phenotypic models that predict the activity of oncogenic pathways

Author:

Huang Erich,Ishida Seiichi,Pittman Jennifer,Dressman Holly,Bild Andrea,Kloos Mark,D'Amico Mark,Pestell Richard G,West Mike,Nevins Joseph R

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Reference14 articles.

1. West, M. et al. Predicting the clinical status of human breast cancer by using gene expression profiles. Proc. Natl. Acad. Sci. USA 98, 11462–11467 (2001).

2. Nevins, J.R. Toward an understanding of the functional complexity of the E2F and Retinoblastoma families. Cell Growth Differ. 9, 585–593 (1998).

3. Dyson, N. The regulation of E2F by pRB-family proteins. Genes Dev. 12, 2245–2262 (1998).

4. Coller, H.A. et al. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc. Natl. Acad. Sci. USA 97, 3260–3265 (2000).

5. Bearss, D.J., Lee, R.L., Troyer, D.A., Pestell, R.G. & Windle, J.J. p21 WAF1/CIP1 deficiency has opposite effects in tumors arising from MMTV-Ras and MMTV-Myc transgenic mice. Cancer Res. 62, 2077–2084 (2002).

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