Clinical and immunologic responses to extracorporeal photopheresis and low-dose IL-2 in patients with steroid refractory chronic graft-versus host disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Transplantation,Hematology
Link
https://www.nature.com/articles/s41409-022-01671-0.pdf
Reference12 articles.
1. Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med. 1998;188:287–96. https://doi.org/10.1084/jem.188.2.287
2. Zorn E, Kim HT, Lee SJ, Floyd BH, Litsa D, Arumugarajah S, et al. Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease. Blood. 2005;106:2903–11. https://doi.org/10.1182/blood-2005-03-1257
3. Chinen T, Kannan AK, Levine AG, Fan X, Klein U, Zheng Y, et al. An essential role for the IL-2 receptor in T(reg) cell function. Nat Immunol. 2016;17:1322–33. https://doi.org/10.1038/ni.3540
4. Matsuoka K, Koreth J, Kim HT, Bascug G, McDonough S, Kawano Y, et al. Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease. Sci Transl Med. 2013;5:179ra143 https://doi.org/10.1126/scitranslmed.3005265
5. Ito S, Bollard KM, Carlsten M, Malenhorst JJ, Biancotto A, Wang E, et al. Ultra-low dose interleukin-2 promotes immune-modulating function of regulatory T cells and natural killer cells in healthy volunteers. Mol Ther. 2014;22:1388–95. https://doi.org/10.1038/mt.2014.50
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1. Recent insights into extracorporeal photopheresis for graft-versus-host disease;Expert Review of Clinical Immunology;2024-02-20
2. A review of low dose interleukin-2 therapy in management of chronic graft-versus-host-disease;Expert Review of Clinical Immunology;2023-11-17
3. Methotrexate/sirolimus/tacrolimus;Reactions Weekly;2023-07-01
4. Chronic graft-versus-host disease. Part II: disease activity grading and therapeutic management;Journal of the American Academy of Dermatology;2022-12
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