Retrospective cohort study comparing the outcomes of intravenous busulfan vs. total-body irradiation after single cord blood transplantation

Author:

Tang Baolin,Zhu Xiaoyu,Zheng Changcheng,Liu Huilan,Hao Siguo,Huang Dongping,Lin Dongjun,Li Nainong,Gao Sujun,Liang Xinquan,Li Jianjun,Huang Lulu,Geng Liangquan,Ding Kaiyang,Wang Xingbing,Yao Wen,Song Kaidi,Zhang Xuhan,Wan Xiang,Zhang Lei,Tong Juan,Sun Guangyu,Wei Zhonglin,Liu Xiaoliang,Wu Yun,Sun Zimin

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Hematology

Reference34 articles.

1. Nagler A, Rocha V, Labopin M, Unal A, Ben Othman T, Campos A, et al. Allogeneic hematopoietic stem-cell transplantation for acute myeloid leukemia in remission: Comparison of intravenous busulfan plus cyclophosphamide(Cy) versus total-body irradiation plus Cy as conditioning regimen-A report from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation. J Clin Oncol. 2013;31:3549–56.

2. Goldstone AH, Richards SM, Lazarus HM, Tallman MS, Buck G, Fielding AK, et al. In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients:final results of the International ALL Trial(MRC UKALL XII/ECOG E2993). Blood. 2008;111:1827–33.

3. Shi-Xia X, Xian-Hua T, Hai-Qin X, Bo F, Xiang-Feng T. Total body irradiation plus cyclophosphamide versus busulphan with cyclophosphamide as conditioning regimen for patients with leukemia undergoing allogeneic stem cell transplantation:A meta-analysis. Leuk Lymphoma. 2010;51:50–60.

4. Hassan M, Ljungman P, Bolme P, Ringdén O, Syrůcková Z, Békàssy A, et al. Busulfan bioavailability. Blood. 1994;84:2144–50.

5. Schiltmeyer B, Klingebiel T, Schwab M, Mürdter TE, Ritter CA, Jenke A, et al. Population pharmacokinetics of oral busulfan in children. Cancer Chemother Pharmacol. 2003;52:209–16.

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