A gemcitabine-based regimen followed by autologous stem cell transplantation show high efficacy and well tolerance in malignant lymphoma

Author:

Liu Huimin,Liu Wei,Li Ru,Jiao Yang,Huang Wenyang,Yi Shuhua,Lv Rui,Deng Shuhui,An Gang,Wang Tingyu,Sui Weiwei,Fu Mingwei,Zhao Yaozhong,Qiu Lugui,Zou DehuiORCID

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Hematology

Reference12 articles.

1. Valdez BC, Nieto Y, Murray D, Li Y, Wang G, Champlin RE, et al. Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. Exp Hematol. 2012;40:800–10. https://doi.org/10.1016/j.exphem.2012.06.001

2. Nieto Y, Thall P, Valdez B, Andersson B, Popat U, Anderlini P, et al. High-dose infusional gemcitabine combined with busulfan and melphalan with autologous stem-cell transplantation in patients with refractory lymphoid malignancies. Biol Blood Marrow Transpl. 2012;18:1677–86. https://doi.org/10.1016/j.bbmt.2012.05.011. e-pub ahead of print 2012/05/31

3. Nieto Y, Popat U, Anderlini P, Valdez B, Andersson B, Liu P, et al. Autologous stem cell transplantation for refractory or poor-risk relapsed Hodgkin’s lymphoma: effect of the specific high-dose chemotherapy regimen on outcome. Biol Blood Marrow Transpl. 2013;19:410–7. https://doi.org/10.1016/j.bbmt.2012.10.029. e-pub ahead of print 2012/11/07

4. Nieto Y, Thall PF, Ma J, Valdez BC, Ahmed S, Anderlini P, et al. Phase II Trial of High-Dose Gemcitabine/Busulfan/Melphalan with Autologous Stem Cell Transplantation for Primary Refractory or Poor-Risk Relapsed Hodgkin Lymphoma. Biol Blood Marrow Transpl. 2018;24:1602–9. https://doi.org/10.1016/j.bbmt.2018.02.020. e-pub ahead of print 2018/03/05

5. Robinson SP, Boumendil A, Finel H, Dreger P, Sureda A, Hermine O, et al. High-dose therapy with BEAC conditioning compared to BEAM conditioning prior to autologous stem cell transplantation for non-Hodgkin lymphoma: no differences in toxicity or outcome. A matched-control study of the EBMT-Lymphoma Working Party. Bone Marrow Transpl. 2018;53:1553–9. https://doi.org/10.1038/s41409-018-0196-3. e-pub ahead of print 2018/06/10

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