Late graft failure with donor-derived GPI-deficient cells in a mixed chimera following allogeneic bone marrow transplantation for severe aplastic anemia

Author:

Katsuya HirooORCID,Yamaguchi Kyosuke,Dung Trung Cao,Sano Haruhiko,Itamura HidekazuORCID,Okamoto Sho,Yoshimura Mariko,Ureshino Hiroshi,Ando Toshihiko,Zaimoku YoshitakaORCID,Nakao Shinji,Kimura Shinya

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Hematology

Reference11 articles.

1. Huss R, Deeg HJ, Gooley T, Bryant E, Leisenring W, Clift R, et al. Effect of mixed chimerism on graft-versus-host disease, disease recurrence and survival after HLA-identical marrow transplantation for aplastic anemia or chronic myelogenous leukemia. Bone Marrow Transplant. 1996;18:767–76.

2. Hill RS, Petersen FB, Storb R, Appelbaum FR, Doney K, Dahlberg S, et al. Mixed hematologic chimerism after allogeneic marrow transplantation for severe aplastic anemia is associated with a higher risk of graft rejection and a lessened incidence of acute graft-versus-host disease. Blood. 1986;67:811–6.

3. Stern M, Passweg JR, Locasciulli A, Socié G, Schrezenmeier H, Békássy AN, et al. Influence of donor/recipient sex matching on outcome of allogeneic hematopoietic stem cell transplantation for aplastic anemia. Transplantation. 2006;82:218–26. https://doi.org/10.1097/01.tp.0000226156.99206.d1.

4. Mochizuki K, Sugimori C, Qi Z, Lu X, Takami A, Ishiyama K, et al. Expansion of donor-derived hematopoietic stem cells with PIGA mutation associated with late graft failure after allogeneic stem cell transplantation. Blood. 2008;112:2160–2. https://doi.org/10.1182/blood-2008-02-141325.

5. Maruyama K, Aotsuka N, Kumano Y, Sato N, Kawashima N, Onda Y, et al. Immune-mediated hematopoietic failure after allogeneic hematopoietic stem cell transplantation: a common cause of late graft failure in patients with complete donor chimerism. Biol Blood Marrow Transplant: J Am Soc Blood Marrow Transplant. 2018;24:43–49. https://doi.org/10.1016/j.bbmt.2017.08.018.

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