Efficacy of prophylactic letermovir for cytomegalovirus reactivation in hematopoietic cell transplantation: a multicenter real-world data

Author:

Mori Yasuo,Jinnouchi Fumiaki,Takenaka Katsuto,Aoki Takatoshi,Kuriyama Takuro,Kadowaki Masanori,Odawara Jun,Ueno Toshiyuki,Kohno Kentaro,Harada Takuya,Yoshimoto Goichi,Takase Ken,Henzan Hideho,Kato Koji,Ito Yoshikiyo,Kamimura Tomohiko,Ohno Yuju,Ogawa Ryosuke,Eto Tetsuya,Nagafuji Koji,Akashi Koichi,Miyamoto ToshihiroORCID

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Hematology

Reference43 articles.

1. Ljungman P, Brand R, Hoek J, de la Camara R, Cordonnier C, Einsele H, et al. Donor cytomegalovirus status influences the outcome of allogeneic stem cell transplant: a study by the European Group for Blood and Marrow Transplantation. Clin Infect Dis. 2014;59:473–81.

2. Teira P, Battiwalla M, Ramanathan M, Barrett AJ, Ahn KW, Chen M, et al. Early cytomegalovirus reactivation remains associated with increased transplant related mortality in the current era: a CIBMTR analysis. Blood. 2016;127:2427–38.

3. Takenaka K, Nishida T, Asano-Mori Y, Oshima K, Ohashi K, Mori T, et al. Cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation is associated with a reduced risk of relapse in patients with acute myeloid leukemia who survived to day 100 after transplantation: the Japan Society for Hematopoietic Cell Transplantation transplantation-related complication working group. Biol Blood Marrow Transplant. 2015;21:2008–16.

4. Boeckh M, Gooley TA, Myerson D, Cunningham T, Schoch G, Bowden RA. Cytomegalovirus pp65 antigenemia-guided early treatment with ganciclovir versus ganciclovir at engraftment after allogeneic marrow transplantation: a randomized double-blind study. Blood. 1996;88:4063–71.

5. Yanada M, Yamamoto K, Emi N, Naoe T, Suzuki R, Taji H, et al. Cytomegalovirus antigenemia and outcome of patients treated with pre-emptive ganciclovir: retrospective analysis of 241 consecutive patients undergoing allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2003;32:801–7.

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