Total body irradiation + fludarabine compared to busulfan + fludarabine as “reduced-toxicity conditioning” for patients with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation in first complete remission: a study by the Acute Leukemia Working Party of the EBMT

Author:

Giebel SebastianORCID,Labopin MyriamORCID,Sobczyk-Kruszelnicka MalgorzataORCID,Stelljes Matthias,Byrne Jenny L.,Fegueux Nathalie,Beelen Dietrich W.,Rovira Montserrat,Spyridonidis AlexandrosORCID,Blaise DidierORCID,Bornhäuser Martin,Karadogan Ihsan,Savani Bipin N.ORCID,Nagler ArnonORCID,Mohty Mohamad,Martin Sonja,Chevallier Patrice,Neubauer Andreas,Damaj Gandhi,Koc Yener,Ganser Arnold,Collin Matthew,Yakoub-Agha Ibrahim,Ozdogu Hakan,Araujo Mercedes Colorado,Itäla-Remes Maija,Orchard Kim,Isaksson Cecilia,Bethge Wolfgang,Martin Hans,Aljurf Mahmoud,Faber Edgar,Caballero Dolores,Zák Pavel,Leleu Xavier,Bay Jacques-Olivier,Rohrlich Pierre-Simon,Kröger Nicolaus,Huynh Anne,Schäfer-Eckart Kerstin,Milpied Noel,Lenhoff Stig,Ho Aloysius,López Jose Luis Bello,Mordini Nicola,Lioure Bruno,Halaburda Kazimierz,Olivieri Attilio,Gedde-Dahl Tobias,Protheroe Rachel,Tischer Johanna,Klammer Matthias,Clausen Johannes,Potter Victoria,Ladetto Marco,Tilly Herve,Deconinck Eric,Brecht Arne,Müller Lutz Peter,Heinicke Thomas,Carrete Juan Pio Torres,Bazarbachi Ali,Reményi Péter,Rubio Marie Thérèse,Fanin Renato,Pérez-Simón Jose Antonio,Niels Murawski,Diez-Martin J. L.,Arat Mutlu,Hermine Olivier,Socié Gerard,Cornelissen Jan J.,Santarone Stella,Guyotat Denis,Bulabois Claude Eric,Bernasconi Paolo,Johansson Jan-Erik,Vrhovac Radovan,Greinix Hildegard,Lorenzo José Luis López,Apte Shashikant,Craddock Charles,Kobbe Guido,Zahrani Mohsen Al,Dreger Peter,Lange Andrzej,Tbakhi Abdelghani,Meijer Ellen,Llamas Carlos Vallejo,Santasusana Josep Maria Ribera,Corradini Paolo,Benedetti Fabio,Rambaldi Alessandro,Gandemer Virginie,Malfuson Jean-Valère,Kaare Ain,Risitano Antonio,Petrini Mario,Selleri Carmine,Wu Depei,

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Hematology

Reference32 articles.

1. Bacigalupo A, Ballen K, Rizzo D, Giralt S, Lazarus H, Ho V, et al. Defining the intensity of conditioning regimens: working definitions. Biol Blood Marrow Transplant. 2009;15:1628–33.

2. Giralt S, Ballen K, Rizzo D, Bacigalupo A, Horowitz M, Pasquini M, et al. Reduced-intensity conditioning regimen workshop: defining the dose spectrum. Report of a workshop convened by the center for international blood and marrow transplant research. Biol Blood Marrow Transplant. 2009;15:367–9.

3. Blaise D, Maraninchi D, Archimbaud E, Reiffers J, Devergie A, Jouet JP, et al. Allogeneic bone marrow transplantation for acute myeloid leukemia in first remission: a randomized trial of a busulfan-Cytoxan versus Cytoxan-total body irradiation as preparative regimen: a report from the Group d’Etudes de la Greffe de Moelle Osseuse. Blood. 1992;79:2578–82.

4. Ringdén O, Ruutu T, Remberger M, Nikoskelainen J, Volin L, Vindeløv L, et al. A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: a report from the Nordic Bone Marrow Transplantation Group. Blood. 1994;83:2723–30.

5. Nagler A, Rocha V, Labopin M, Unal A, Ben Othman T, Campos A, et al. Allogeneic hematopoietic stem-cell transplantation for acute myeloid leukemia in remission: comparison of intravenous busulfan plus cyclophosphamide (Cy) versus total-body irradiation plus Cy as conditioning regimen–a report from the acute leukemia working party of the European group for blood and marrow transplantation. J Clin Oncol. 2013;31:3549–56.

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