p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene
Author:
Affiliation:
1. Centro de Investigaciones Biológicas (CIB‐CSIC) Ramiro de Maeztu 9 Madrid 28040 Spain
2. the Breakthrough Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research 237 Fulham Road London SW3 6JB UK
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1038/sj.embor.7400587
Reference37 articles.
1. The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells
2. Role of the human RAD51 protein in homologous recombination and double-stranded-break repair
3. DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis
4. p53's double life: transactivation-independent repression of homologous recombination
5. p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair
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