Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints-Reference-Cited by-同舟云学术

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

Published:2016-02-17 Issue:1 Volume:7 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Koyama Shohei,Akbay Esra A.,Li Yvonne Y.,Herter-Sprie Grit S.,Buczkowski Kevin A.,Richards William G.,Gandhi Leena,Redig Amanda J.,Rodig Scott J.,Asahina Hajime,Jones Robert E.,Kulkarni Meghana M.,Kuraguchi Mari,Palakurthi Sangeetha,Fecci Peter E.,Johnson Bruce E.,Janne Pasi A.,Engelman Jeffrey A.,Gangadharan Sidharta P.,Costa Daniel B.,Freeman Gordon J.,Bueno Raphael,Hodi F. Stephen,Dranoff Glenn,Wong Kwok-Kin,Hammerman Peter S.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms10501.pdf

Reference37 articles.

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2. Brahmer, J. R. et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N. Engl. J. Med. 366, 2455–2465 (2012).

3. Page, D. B., Postow, M. A., Callahan, M. K., Allison, J. P. & Wolchok, J. D. Immune modulation in cancer with antibodies. Annu. Rev. Med. 65, 185–202 (2014).

4. Keir, M. E., Butte, M. J., Freeman, G. J. & Sharpe, A. H. PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 26, 677–704 (2008).

5. Pardoll, D. M. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12, 252–264 (2012).

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