Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension-Reference-Cited by-同舟云学术

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

Published:2016-01-20 Issue:1 Volume:7 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Cox Charles D.,Bae Chilman,Ziegler Lynn,Hartley Silas,Nikolova-Krstevski Vesna,Rohde Paul R.,Ng Chai-Ann,Sachs Frederick^ORCID,Gottlieb Philip A.,Martinac Boris^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms10366.pdf

Reference70 articles.

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2. Coste, B. et al. Piezo proteins are pore-forming subunits of mechanically activated channels. Nature 483, 176–181 (2012) .

3. Ikeda, R. & Gu, J. G. Piezo2 channel conductance and localization domains in Merkel cells of rat whisker hair follicles. Neurosci. Lett. 7, 210–215 (2014) .

4. Woo, S. H. et al. Piezo2 is required for Merkel-cell mechanotransduction. Nature 509, 622–626 (2014) .

5. Bae, C., Gnanasambandam, R., Nicolai, C., Sachs, F. & Gottlieb, P. A. Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1. Proc. Natl Acad. Sci. USA 110, E1162–E1168 (2013) .

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