Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A-Reference-Cited by-同舟云学术

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A

Published:2010-10-05 Issue:1 Volume:1 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Ogawa Yasushi,Nonaka Yosuke,Goto Toshiyasu,Ohnishi Eriko,Hiramatsu Toshiyuki,Kii Isao,Yoshida Miyo,Ikura Teikichi,Onogi Hiroshi,Shibuya Hiroshi,Hosoya Takamitsu,Ito Nobutoshi,Hagiwara Masatoshi

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms1090.pdf

Reference58 articles.

1. Becker, W., Weber, Y., Wetzel, K., Eirmbter, K., Tejedor, F. J. & Joost, H. G. Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases. J. Biol. Chem. 273, 25893–25902 (1998).

2. Wiseman, F. K., Alford, K. A., Tybulewicz, V. L. & Fisher, E. M. Down syndrome—recent progress and future prospects. Hum. Mol. Genet. 18, R75–83 (2009).

3. Sherman, S. L., Allen, E. G., Bean, L. H. & Freeman, S. B. Epidemiology of Down syndrome. Ment. Retard. Dev. Disabil. Res. Rev. 13, 221–227 (2007).

4. Antonarakis, S. E. & Epstein, C. J. The challenge of Down syndrome. Trends Mol. Med. 12, 473–479 (2006).

5. Guimera, J. et al. A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region. Hum. Mol. Genet. 5, 1305–1310 (1996).

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