A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/ncomms10660.pdf
Reference54 articles.
1. Lanner, F. Lineage specification in the early mouse embryo. Exp. Cell. Res. 321, 32–39 (2014).
2. Aladjem, M. I. et al. ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Curr. Biol. 8, 145–155 (1998).
3. Hong, Y. & Stambrook, P. J. Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation. Proc. Natl Acad. Sci. USA 101, 14443–14448 (2004).
4. Tichy, E. D. & Stambrook, P. J. DNA repair in murine embryonic stem cells and differentiated cells. Exp. Cell. Res. 314, 1929–1936 (2008).
5. van der Laan, S., Tsanov, N., Crozet, C. & Maiorano, D. High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency. Mol. Cell. 52, 366–379 (2013).
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