The role of kinetic context in apparent biased agonism at GPCRs-Reference-Cited by-同舟云学术

The role of kinetic context in apparent biased agonism at GPCRs

Published:2016-02-24 Issue:1 Volume:7 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Klein Herenbrink Carmen,Sykes David A.,Donthamsetti Prashant,Canals Meritxell,Coudrat Thomas,Shonberg Jeremy,Scammells Peter J.,Capuano Ben,Sexton Patrick M.^ORCID,Charlton Steven J.,Javitch Jonathan A.,Christopoulos Arthur,Lane J. Robert

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms10842.pdf

Reference64 articles.

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4. Overington, J. P., Al-Lazikani, B. & Hopkins, A. L. How many drug targets are there? Nat. Rev. Drug Discov. 5, 993–996 (2006).

5. Violin, J. D., Crombie, A. L., Soergel, D. G. & Lark, M. W. Erratum: biased ligands at G protein-coupled receptors: promise and progress. Trends Pharmacol. Sci. 35, 308–316 (2014).

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