Cryptic t(3;8)(q27;q24) and/or MYC-BCL6 linkage associated with MYC expression by immunohistochemistry is frequent in multiple-hit B-cell lymphomas
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Hematology
Link
http://www.nature.com/articles/bcj201759.pdf
Reference15 articles.
1. Aukema SM, Siebert R, Schuuring E, van Imhoff GW, Kluin-Nelemans HC, Boerma EJ et al. Double-hit B-cell lymphomas. Blood 2011; 117: 2319–2331.
2. Akasaka T, Akasaka H, Yonetani N, Ohno H, Yamabe H, Fukuhara S et al. Refinement of the BCL2/immunoglobulin heavy chain fusion gene in t(14;18)(q32;q21) by polymerase chain reaction amplification for long targets. Genes Chromosomes Cancer 1998; 21: 17–29.
3. Gu K, Chan WC, Hawley RC . Practical detection of t(14;18)(IgH/BCL2 in follicular lymphoma. Arch Pathol Lab Med 2008; 132: 1355–1361.
4. Bertrand P, Bastard C, Maingonnat C, Jardin F, Maisonneuve C, Courel MN et al. Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas. Leukemia 2007; 21: 515–523.
5. Munoz-Marmol AM, Sanz C, Tapia G, Marginet R, Ariza A, Mate JL . MYC status determination in aggressive B-cell lymphoma: the impact of FISH probe selection. Histopathology 2013; 63: 418–424.
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1. Testing for t(3;8) in MYC/BCL6-rearranged large B-cell lymphoma identifies a high-risk subgroup with inferior survival;Blood;2024-07-04
2. Histone acetylation dynamics modulates chromatin conformation and allele-specific interactions at oncogenic loci;Nature Genetics;2021-05
3. Coexistence of MYC/BCL2 double-hit of t(8;14)(q24;q32) and t(14;18)(q32;q21) and that of t(8;22)(q24;q11) and t(14;18) in advanced-stage high-grade B cell lymphoma;Annals of Hematology;2020-09-07
4. Lymphomas with pseudo–double-hit BCL6-MYC translocations due to t(3;8)(q27;q24) are associated with a germinal center immunophenotype, extranodal involvement, and frequent BCL2 translocations;Human Pathology;2018-10
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