Mechanotransduction gone awry
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm2597.pdf
Reference90 articles.
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3. Ingber, D. E. Cellular mechanotransduction: putting all the pieces together again. FASEB J. 20, 811–827 (2006).
4. Orr, A. W., Helmke, B. P., Blackman, B. R. & Schwartz, M. A. Mechanisms of mechanotransduction. Dev. Cell 10, 11–20 (2006).
5. Vogel, V. & Sheetz, M. Local force and geometry sensing regulate cell functions. Nature Rev. Mol. Cell Biol. 7, 265–275 (2006). This is a comprehensive review of the literature on how physical cues in the microenvironment of a eukaryotic cell are sensed and converted to biochemical signals that define cell shape and regulate cell growth, differentiation and survival.
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