Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation-Reference-Cited by-同舟云学术

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Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation

Published:2015-06-16 Issue:1 Volume:6 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Whalley Helen J.,Porter Andrew P.,Diamantopoulou Zoi,White Gavin R. M.,Castañeda-Saucedo Eduardo,Malliri Angeliki

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms8437.pdf

Reference59 articles.

1. Blagden, S. P. & Glover, D. M. Polar expeditions - provisioning the centrosome for mitosis. Nat. Cell Biol. 5, 505–511 (2003).

2. Fry, A. M. et al. C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle–regulated protein kinase Nek2. J. Cell Biol. 141, 1563–1574 (1998).

3. Tanenbaum, M. E. & Medema, R. H. Mechanisms of centrosome separation and bipolar spindle assembly. Dev. Cell 19, 797–806 (2010).

4. Ferenz, N. P., Gable, A. & Wadsworth, P. Mitotic functions of kinesin-5. Semin. Cell Dev. Biol. 21, 255–259 (2010).

5. Tanenbaum, M. E., Macurek, L., Galjart, N. & Medema, R. H. Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly. EMBO J. 27, 3235–3245 (2008).

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