The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

Author:

Papadopoulou Aikaterini S,Dooley James,Linterman Michelle A,Pierson Wim,Ucar Olga,Kyewski Bruno,Zuklys Saulius,Hollander Georg A,Matthys Patrick,Gray Daniel H D,De Strooper Bart,Liston Adrian

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Reference47 articles.

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2. Itoh, M. et al. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162, 5317–5326 (1999).

3. King, C.C. et al. Viral infection of the thymus. J. Virol. 66, 3155–3160 (1992).

4. Anz, D. et al. Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus. J. Immunol. 182, 6044–6050 (2009).

5. Aronson, M. Hypothesis: involution of the thymus with aging–programmed and beneficial. Thymus 18, 7–13 (1991).

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