Small silencing RNAs: an expanding universe
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg2504.pdf
Reference228 articles.
1. Fire, A. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806–811 (1998). The landmark discovery of dsRNA as the trigger for RNAi.
2. Voinnet, O. Non-cell autonomous RNA silencing. FEBS Lett. 579, 5858–5871 (2005).
3. Grishok, A., Tabara, H. & Mello, C. C. Genetic requirements for inheritance of RNAi in C. elegans. Science 287, 2494–2497 (2000).
4. Hamilton, A. J. & Baulcombe, D. C. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 286, 950–952 (1999). This paper identified small RNAs — now known as siRNAs — as the guides for post-transcriptional gene silencing in plants.
5. Zamore, P. D., Tuschl, T., Sharp, P. A. & Bartel, D. P. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101, 25–33 (2000). This paper and reference 6 showed that siRNAs are the specificity determinants for endonucleolytic cleavage of RNA targets by RISC.
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