Structure-based inhibitors of tau aggregation
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
http://www.nature.com/articles/nchem.2889.pdf
Reference32 articles.
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3. Goedert, M., Eisenberg, D. S. & Crowther, R. A. Propagation of tau aggregates and neurodegeneration. Annu. Rev. Neurosci. 40, 189–210 (2017).
4. Schwarz, A. J. et al. Regional profiles of the candidate tau PET ligand recapitulate key features of Braak histopathological stages. Brain 139, 1539–1550 (2016).
5. Manczak, M. & Reddy, P. H. Abnormal interaction of oligomeric amyloid-β with phosphorylated tau: implications to synaptic dysfunction and neuronal damage. J. Alzheimers Dis. 36, 285–295 (2013).
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