De novo design of a hyperstable non-natural protein–ligand complex with sub-Å accuracy-Reference-Cited by-同舟云学术

De novo design of a hyperstable non-natural protein–ligand complex with sub-Å accuracy

Published:2017-08-21 Issue:12 Volume:9 Page:1157-1164
ISSN:1755-4330
Container-title:Nature Chemistry
language:en
Short-container-title:Nature Chem

Author:

Polizzi Nicholas F.^ORCID,Wu Yibing,Lemmin Thomas,Maxwell Alison M.,Zhang Shao-Qing,Rawson Jeff,Beratan David N.^ORCID,Therien Michael J.^ORCID,DeGrado William F.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Chemical Engineering,General Chemistry

Link

http://www.nature.com/articles/nchem.2846.pdf

Reference49 articles.

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3. Nanda, V. & Koder, R. L. Designing artificial enzymes by intuition and computation. Nat. Chem. 2, 15–24 (2010).

4. Peacock, A. F. A. Incorporating metals into de novo proteins. Curr. Opin. Chem. Biol. 17, 934–939 (2013).

5. Huang, P.-S. et al. High thermodynamic stability of parametrically designed helical bundles. Science 346, 481–485 (2014).

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