Variation in the α 5 nicotinic acetylcholine receptor subunit gene predicts cigarette smoking intensity as a function of nicotine content-Reference-Cited by-同舟云学术

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Variation in the α 5 nicotinic acetylcholine receptor subunit gene predicts cigarette smoking intensity as a function of nicotine content

Published:2013-01-29 Issue:1 Volume:14 Page:70-76
ISSN:1470-269X
Container-title:The Pharmacogenomics Journal
language:en
Short-container-title:Pharmacogenomics J

Author:

MacQueen D A,Heckman B W,Blank M D,Janse Van Rensburg K,Park J Y,Drobes D J,Evans D E

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Genetics,Molecular Medicine

Link

http://www.nature.com/articles/tpj201250.pdf

Reference56 articles.

1. The Tobacco and Genetics Consortium.. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet 2010; 42: 441–447.

2. Bierut LJ . Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24–25. Trends Pharmacol Sci 2010; 31: 46–51.

3. Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PA et al. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet 2007; 16: 36–49.

4. Bierut LJ, Stitzel JA, Wang JC, Hinrichs AL, Grucza RA, Xuei X et al. Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry 2008; 165: 1163–1171.

5. Kuryatov A, Berrettini W, Lindstrom J . Acetylcholine receptor (AChR) alpha5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (alpha4beta2)alpha5 AChR function. Mol Pharmacol 2011; 79: 119–125.

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