Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4-Reference-Cited by-同舟云学术

Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4

Published:2017-05-08 Issue:6 Volume:23 Page:742-752
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Zhao Guang-Nian,Zhang Peng,Gong Jun,Zhang Xiao-Jing,Wang Pi-Xiao,Yin Miao,Jiang Zhou,Shen Li-Jun,Ji Yan-Xiao,Tong Jingjing,Wang Yutao,Wei Qiao-Fang,Wang Yong,Zhu Xue-Yong,Zhang Xin,Fang Jing,Xie Qingguo,She Zhi-Gang,Wang Zhihua,Huang Zan,Li Hongliang

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.4334.pdf

Reference78 articles.

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2. Younossi, Z.M. et al. Global epidemiology of non-alcoholic fatty liver disease—meta-analytic assessment of prevalence, incidence and outcomes. Hepatology 64, 73–84 (2016).

3. Cohen, J.C., Horton, J.D. & Hobbs, H.H. Human fatty liver disease: old questions and new insights. Science 332, 1519–1523 (2011).

4. Byrne, C.D. & Targher, G. NAFLD: a multisystem disease. J. Hepatol. 62 (Suppl. 1), S47–S64 (2015).

5. LaBrecque, D.R. et al. World Gastroenterology Organization global guidelines: non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. J. Clin. Gastroenterol. 48, 467–473 (2014).

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