CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
https://www.nature.com/articles/s41556-022-00946-4.pdf
Reference84 articles.
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2. Willnow, D. et al. Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche. Nature 597, 87–91 (2021).
3. Puri, S., Folias, A. E. & Hebrok, M. Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease. Cell Stem Cell 16, 18–31 (2015).
4. Yuan, S., Norgard, R. J. & Stanger, B. Z. Cellular plasticity in cancer. Cancer Discov. 9, 837–851 (2019).
5. Tata, P. R. et al. Developmental history provides a roadmap for the emergence of tumor plasticity. Dev. Cell 44, 679–693.e5 (2018).
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