Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes-Reference-Cited by-同舟云学术

Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes

Published:2023-01-12 Issue: Volume: Page:
ISSN:1465-7392
Container-title:Nature Cell Biology
language:en
Short-container-title:Nat Cell Biol

Author:

Sparbier Christina E.,Gillespie Andrea,Gomez Juliana,Kumari Nishi,Motazedian Ali,Chan Kah Lok^ORCID,Bell Charles C.^ORCID,Gilan Omer,Chan Yih-Chih^ORCID,Popp Sarah,Gough Daniel J.,Eckersley-Maslin Melanie A.^ORCID,Dawson Sarah-Jane^ORCID,Lehner Paul J.^ORCID,Sutherland Kate D.,Ernst Patricia^ORCID,McGeehan Gerard M.,Lam Enid Y. N.^ORCID,Burr Marian L.^ORCID,Dawson Mark A.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology

Link

https://www.nature.com/articles/s41556-022-01056-x.pdf

Reference102 articles.

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3. Hughes, A. L., Kelley, J. R. & Klose, R. J. Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation. Biochim. Biophys. Acta Gene Regul. Mech. 1863, 194567 (2020).

4. Cenik, B. K. & Shilatifard, A. COMPASS and SWI/SNF complexes in development and disease. Nat. Rev. Genet. 22, 38–58 (2021).

5. Laugesen, A., Hojfeldt, J. W. & Helin, K. Molecular mechanisms directing PRC2 recruitment and H3K27 methylation. Mol. Cell 74, 8–18 (2019).

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