Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
http://www.nature.com/articles/s41556-018-0271-4.pdf
Reference44 articles.
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2. Pagliuca, F. W. et al. Generation of functional human pancreatic β cells in vitro. Cell. 159, 428–439 (2014).
3. Rezania, A. et al. Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nat. Biotech. 32, 1121–1133 (2014).
4. Russ, H. A. et al. Controlled induction of human pancreatic progenitors produces functional β-like cells in vitro. EMBO J. 34, 1759–1772 (2015).
5. Yoshihara, E. et al. ERRɣ is required for the metabolic maturation of therapeutically functional glucose-responsive β cells. Cell. Metab. 23, 622–634 (2016).
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