An E3 ligase and autophagy adaptor regulates tau proteostasis through nested phase separation
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Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41556-024-01466-z.pdf
Reference5 articles.
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2. Lovestam, S. et al. Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy. eLife 11, e76494 (2022). A research article about in vitro assembly of tau fibrils that are identical to those detected in some neurodegenerative diseases.
3. Margolin, D. H. et al. Ataxia, dementia, and hypogonadotropism caused by disordered ubiquitination. N. Engl. J. Med. 368, 1992–2003 (2013). A research article identifying missense mutations in TRIAD3A in individuals with dementia, thereby linking ubiquination dysfunction to neurodegenerative disease.
4. Kirkin, V. & Rogov, V. V. A diversity of selective autophagy receptors determines the specificity of the autophagy pathway. Mol. Cell 76, 268–285 (2019). A review article about autophagy adaptors and how their selectivity regulates specificity.
5. Van Acker, Z. P., Bretou, M. & Annaert, W. Endo-lysosomal dysregulations and late-onset Alzheimer's disease: impact of genetic risk factors. Mol. Neurodegener. 14, 20 (2019). A review article discussing how endolysosomal dysfunction contributes to neurodegeneration onset in Alzheimer disease.
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