PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
http://www.nature.com/articles/s41556-019-0409-z.pdf
Reference51 articles.
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2. Lee, Y. R., Chen, M. & Pandolfi, P. P. The functions and regulation of the PTEN tumour suppressor: new modes and prospects. Nat. Rev. Mol. Cell Biol. 19, 547–562 (2018).
3. Naderali, E. et al. Regulation and modulation of PTEN activity. Mol. Biol. Rep. 45, 2869–2881 (2018).
4. Song, M. S. et al. Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner. Cell 144, 187–199 (2011).
5. Shen, S. M. et al. AIF inhibits tumor metastasis by protecting PTEN from oxidation. EMBO Rep. 16, 1563–1580 (2015).
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