STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
https://www.nature.com/articles/s41556-023-01185-x.pdf
Reference61 articles.
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2. Woo, S. R. et al. STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. Immunity 41, 830–842 (2014).
3. Zhang, Z.-D. & Zhong, B. Regulation and function of the cGAS-MITA/STING axis in health and disease. Cell Insight 1, 100001 (2022).
4. Yum, S., Li, M. H., Frankel, A. E. & Chen, Z. J. J. Roles of the cGAS-STING pathway in cancer immunosurveillance and immunotherapy. Annu. Rev. Cancer Biol. 3, 323–344 (2019).
5. Kwon, J. & Bakhoum, S. F. The cytosolic DNA-sensing cGAS-STING pathway in cancer. Cancer Discov. 10, 26–39 (2020).
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