CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep22024.pdf
Reference33 articles.
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2. Reddy, M. A., Francis, P. J., Berry, V., Bhattacharya, S. S. & Moore, A. T. Molecular genetic basis of inherited cataract and associated phenotypes. Survey of ophthalmology 49, 300–315 (2004).
3. Holmes, J. M., Leske, D. A., Burke, J. P. & Hodge, D. O. Birth prevalence of visually significant infantile cataract in a defined U.S. population. Ophthalmic epidemiology 10, 67–74 (2003).
4. Gao, X. et al. A novel mutation in the connexin 50 gene (GJA8) associated with autosomal dominant congenital nuclear cataract in a Chinese family. Current eye research 35, 597–604 (2010).
5. Chen, C. et al. A novel Cx50 (GJA8) p.H277Y mutation associated with autosomal dominant congenital cataract identified with targeted next-generation sequencing. Graefe’s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 253, 915–924 (2015).
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